From clinical AI agents to single-cell foundation models — selected work across biomedical computing, multimodal learning, and applied ML.
A multimodal AI agent integrating traditional Chinese medicine's four diagnostic methods (inspection, auscultation, inquiry, palpation) with modern machine learning. Built on exclusive clinical datasets from Longhua Hospital in collaboration with Shanghai University of TCM.
Target: CBS-class journal (CAS Q1 Top, IF 18.1) — 1st Author
Spatiotemporal transformer with graph fusion for DCE-MRI breast tumor segmentation. Collaboration with Tsinghua SIGS (Prof. Peiwu Qin's team). Achieves state-of-the-art on 2 public breast DCE-MRI datasets, outperforming existing 2D, 3D, and 4D approaches.
Published in Cyborg and Bionic Systems · 3rd Author
First foundation model-based world simulator for the tumor immune microenvironment. A 12-layer trajectory-aware Transformer autoregressively pre-trained on 12.4M single cells, achieving Pearson r=0.914 on cell-state transition prediction. Cross-cancer transfer module lifts ICB response AUC to 0.891 across 14 cohorts and 7 cancer types.
Under Review at Nature Communications · 4th Author · Collaboration with BIT
Regional power demand prediction system using ensemble ML (LSTM, LightGBM, Prophet) and LLM semantic analysis. Built multi-source data fusion models achieving MAPE < 3%, R² > 0.97 across multiple scenarios.
Huadian Energy Research Center · Project Manager
Initialization-free human pose estimation from IMU sensors using Diffusion Models with physics-based dynamics constraints. Designed for rehabilitation medicine and sports monitoring applications.
HKUST(GZ) SIIE Lab · Research Assistant
A multi-center evidence synthesis targeting CA: A Cancer Journal for Clinicians (IF ~500+, the highest-impact medical journal in the world). Integrates bone-sarcoma imaging, pathology, and follow-up data from 6 Class-A hospitals to build a cross-region, cross-age, cross-subtype global epidemiological portrait and clinical decision pathway.
In Preparation · Co-First Author (later in order) · With Dr. Mingyang Jiang (NUS) · Target submission Summer 2026
A bone-sarcoma imaging / pathology / follow-up data platform jointly built by 6 Class-A hospitals. Responsible for compliant ingestion, cross-center schema alignment, and a tri-modal (imaging-pathology-clinical) data pipeline that serves as the data backbone for multi-center evidence synthesis.
Infrastructure work · 6 Class-A hospitals · Powers the CA Cancer Journal review and downstream modeling
A tech company I co-founded, working in the ed-tech space. Closed an end-to-end loop from product definition and engineering to operations and go-to-market — independently. Cumulative net profit of 1M+ RMB to date. A real-world experience that runs both the "research" and "product" mental models on the same brain.
Co-founder · 2023 – Present · Cumulative net profit 1M+ RMB